Mountain Valley MD Studies Yr-Finish Enterprise Replace and Progress in Core Platform Commercialization


TORONTO, December 24, 2025–(BUSINESS WIRE)–Mountain Valley MD Holdings Inc. (the “Firm” or “MVMD”) (CSE: MVMD) (OTCQB: MVMDF) (FRA: 20MP) supplies a year-end enterprise replace on its commercialization progress throughout its three core areas of focus:

  1. Nutraceuticals – Improvements by way of the Firm’s Quicksome™ know-how, designed to enhance the administration and efficacy of nutraceutical well being and wellness merchandise;

  2. Agriculture – The Firm’s licensed Agrarius agricultural plant signaling know-how, designed to organically drive elevated crop yields, scale back fertilizer and pesticide utilization the place desired, and improve plant well being; and

  3. Husbandry Animals and Aquatic Species – The applying of solubilized drug formulations by way of the Firm’s Quicksol™ know-how, designed to positively impression the well being of husbandry animals and aquatic species.

“All through 2025, we have now remained centered on disciplined execution throughout every of our enterprise strains,” stated Dennis Hancock, President and CEO of Mountain Valley MD. “We consider the progress we have now made in product growth, discipline validation, and business foundations positions the Firm for the subsequent section of measured development.”

NUTRACEUTICALS

Quicksome™ Know-how, Commercialization, and Enterprise Improvement Progress

MVMD’s patented liposomal Quicksome™ know-how makes use of proprietary formulations and stabilizing brokers to encapsulate energetic components with the objective of optimizing molecule supply in sublingual nutraceutical functions. The Firm’s Quicksome™ platform continues to concentrate on delivering molecules the place enhanced efficacy, exact dosing, diminished variability, and dose sparing are valued.

“Our Quicksome™ know-how continues to show to us its adaptability throughout a number of product formulations,” Mr. Hancock famous. “We consider the platform’s supply traits and dose-sparing potential stay compelling for companions looking for differentiated merchandise in aggressive wellness classes.”

MVMD continues to advance its nutraceutical technique by way of its unique manufacturing and licensing association with a U.S.-based GMP manufacturing associate (the “Lead Producer”), which maintains GMP and OTC drug manufacturing capabilities and has put in proprietary tools to help Quicksome™ sublingual and dermal formulations.

The Lead Producer continues to work with the Firm to help manufacturing obligations below MVMD’s license settlement with Circadian Wellness Corp. (“Circadian”), in addition to MVMD’s proprietary “Mountains Of…” product line and different enterprise growth initiatives. Throughout 2025, scaled manufacturing and business exercise continued for Circadian’s “Eons Dialed” and “Eons Deeper Sleep” sublingual merchandise, each incorporating Quicksome™ know-how. Circadian reported continued constructive client reception and gross sales volumes of its Quicksome™-based merchandise through the yr.

In parallel, MVMD has continued enterprise growth initiatives to safe further nutraceutical licensing partnerships by way of the event of novel formulation work for brand spanking new shoppers in a number of human profit areas together with novel sizzling flash and night time sweat signs reduction in peri menopausal and post-menopausal ladies, post-workout muscle restoration, anti-inflammation, and joint well being. The Firm additionally stays engaged with a U.S.-based multi-level advertising shopper for a novel fenugreek glycosides testosterone formulation using Quicksome™ quick-dissolve pill know-how. The formulation has supported documented efficiency in male topics, and iterative product evaluations associated to style and dissolution have continued, with business discussions anticipated to advance as associate assessment processes progress. Extra shopper discussions have taken place within the fourth quarter and the Firm expects the launch of a fenugreek glycosides testosterone formulation by way of a licensee within the first half of 2026.

The Firm’s “Mountains Of…” proprietary model continues to carry U.S. trademark safety throughout a number of product classes, together with Sleep, Vitality, Aid, Libido, and Lean, to help ongoing GMP pattern growth and enterprise growth actions. Distribution companions might elect to market MVMD’s branded merchandise or pursue proprietary white-label variations below their very own manufacturers.

AGRICULTURE

Agrarius Enterprise Improvement and Commercialization Progress

“We consider the continued validation of Agrarius throughout various crops and geographies reinforces its potential function in sustainable agricultural practices,” stated Mr. Hancock. “Our focus stays on constructing a powerful, data-driven basis to help long-term business adoption.”

MVMD continues to advance commercialization in its agricultural division, which is concentrated on the licensed distribution of the Agrarius™ plant signaling know-how. Below its unique license settlement with Agrarius Corp. (“AC”), MVMD holds the unique rights to promote the Agrarius product all through North America, Central America, South America, and the Caribbean (the “Unique Territory”).

The Agrarius product is blended with water or different agricultural inputs on the level of software and utilized through sprayer at focused levels of a plant’s lifecycle. Agrarius has been examined throughout quite a few crops and has demonstrated its skill to naturally improve yields, enhance plant resilience, and help diminished fertilizer utilization, with outcomes various by crop and atmosphere.

Brazil Citrus Trials, Together with Optimistic Youthful Tree Outcomes

MVMD has been working with a client-directed third-party agricultural associate, FARMATAC, in Brazil to evaluate the impression of the applying of the Agrarius product on each mature and younger citrus orchards. FARMATAC has in depth expertise designing and managing superior citrus trials and has accomplished the contracted evaluations in business citrus orchards.

The Firm beforehand reported the next outcomes from mature Hamlin and Valencia orange bushes:

  • Hamlin Selection: Agrarius-treated orchards demonstrated improved plant situation and a productiveness improve of roughly 15% per hectare. Juice yield evaluation confirmed that the handled oranges required 20 fewer containers to supply one ton of juice in comparison with the management, leading to an approximate complete yield improve of twenty-two%. Unbiased agronomists additionally noticed a visible discount in signs related to Huanglongbing (HLB), also called citrus greening illness.

  • Valencia Selection: The Agrarius-treated block achieved a 49% common yield improve. Handled bushes additionally exhibited stronger vigor and cover density, in line with improved nutrient uptake and photosynthetic exercise.

Constructing on the mature orchard outcomes, newly accomplished trials on further citrus blocks, together with youthful orchards and extra varietals on the shopper’s website, have now demonstrated additional compelling outcomes. In trials that included remedies on youthful bushes, Agrarius-treated areas confirmed materially stronger plant vigor, improved flowering and fruit set, enhanced resilience to emphasize, together with during times of drier rising circumstances, and considerably larger productiveness when in comparison with management blocks. Notably, productiveness positive factors of larger than 50 % have been recorded in Pera varietals, alongside outcomes in line with prior Hamlin and Valencia efficiency, reinforcing the potential lifecycle impression of Agrarius when utilized earlier in orchard growth and its potential function in serving to mitigate yield variability below more and more difficult weather conditions.

“The Brazil citrus trial demonstrates to us that Agrarius™, below actual farm circumstances and third-party monitoring, delivered substantial yield enhancements, stronger plant well being, and significant mitigation of Greening stress in citrus,” continued Hancock. “Our agronomy group not too long ago reviewed the trial outcomes with the shopper’s management group and it’s believed the findings will help business growth in 2026, positioning Agrarius as a high-impact, low-disruption device for Brazilian citriculture.”

The Firm believes that the continued commentary of diminished seen HLB signs throughout its Brazil citrus packages, together with in youthful orchards, represents one of the vital significant indicators rising from its citrus discipline work to this point. These outcomes are in line with citrus trials beforehand reported by the Firm and help the potential lifecycle relevance of Agrarius in orchards impacted by citrus greening illness.

“HLB has basically altered citrus manufacturing in lots of areas, and producers nonetheless face the truth that there isn’t any recognized remedy,” stated Hancock. “Seeing comparable developments not solely in mature bushes but in addition in youthful orchards strengthens our view that, if sustained, Agrarius may grow to be an essential natural device to assist growers handle greening strain whereas constructing more healthy, extra productive orchards over time.”

Broad Crop Validation and LATAM Growth

Along with citrus, Agrarius trials performed through the yr throughout key crops in Brazil and Colombia in partnership with universities, non-public agronomy labs, and farmer networks continued to show to the Firm constructive outcomes, together with:

  • Corn – Yield positive factors of roughly 14.8 % and 11.2 % in UNESP trials, related to improved chlorophyll focus and root growth.

  • Sugarcane – Yield enhancements of 8 to 12 tons per hectare, elevated sugar content material, and diminished pest injury in Agroquatro trials, alongside improved early growth in seedling clone research.

  • Soybeans – Common yield positive factors of 6.34 sacs per hectare throughout 14 farmer validations, with high-performance producers attaining positive factors exceeding 15 %.

  • Cotton – Will increase in bolls per plant and total yield supported by improved photosynthetic effectivity.

  • Potatoes – Productiveness will increase of roughly 18.5 % in summer season harvest trials.

Of explicit observe, throughout prolonged dry durations noticed in Brazil discipline packages, Agrarius-treated crops skilled notably decrease yield losses than untreated controls, supporting the product’s potential to enhance water-use effectivity and keep productiveness below drought stress as a part of an built-in agronomic program.

“The latest citrus trialing exercise has produced outcomes that reinforce what we’re seeing throughout a number of crops in Brazil, that Agrarius is just not solely driving yield enchancment, but in addition serving to crops keep productive when circumstances are lower than preferrred,” continued Hancock. “In markets the place growers face rising local weather variability, this sort of resilience might be simply as essential as top-line yield positive factors.”

In Colombia, MVMD is finishing its large-scale pasture grass productiveness program in partnership with FEDEGAN, the nationwide cattle growers’ federation representing roughly 43 million hectares of pastureland, and the Nationwide College of Colombia, with preliminary outcomes demonstrating improved vegetation well being, quicker regrowth, and enhanced pasture high quality, supported by satellite tv for pc evaluation and laboratory validation. Remaining outcomes are anticipated within the first quarter of 2026.

HUSBANDRY ANIMALS / AQUATIC SPECIES

Soluvec™ 1% Commercialization Replace and Strategic Evaluation

MVMD has utilized its patented Quicksol™ solubilization know-how to ivermectin to create its Soluvec™ 1% formulation, which was designed to supply a safer and more practical answer for administration throughout husbandry animals and aquatic species. The Soluvec™ 1% formulation has demonstrated nine-month stability at room and refrigerated temperatures by way of third-party validation and stays the Firm’s major Quicksol™-based business asset.

The Firm’s commercialization technique for Soluvec™ 1% has been to advance the know-how by way of third-party licensing. In Bangladesh, MVMD entered into an unique license settlement with an arm’s size, privately held associate to fabricate and distribute Soluvec™ 1% merchandise in injectable and feed coating codecs, in return for royalty funds based mostly on internet gross sales. As beforehand disclosed, the licensee has produced roughly 200 tonnes of Soluvec™ 1% coated fish feed and distributed product by way of native channels.

Whereas this exercise represented an essential first step in demonstrating large-scale manufacturing and software of the Soluvec™ formulation, royalty revenues and total business traction throughout 2025 have remained under administration’s expectations. Exterior market disruption, together with impacts from Cyclone Remal in 2024, has affected trade circumstances within the area, and MVMD continues to evaluate the best pathway to advance broader adoption of the know-how.

“We proceed to consider within the power of the underlying science and formulation behind Soluvec™,” acknowledged Hancock. “On the similar time, we acknowledge that realizing its business potential requires companions with the precise operational scale, market attain, and strategic alignment.”

As a part of its evaluation, the Firm is endeavor a strategic assessment of its Soluvec™ 1% licensing construction, together with evaluating choices to switch or restructure territorial exclusivity in Bangladesh, topic to contractual rights and ongoing discussions between related events. The target is to make sure MVMD has the flexibleness to work with companions greatest positioned to drive efficient commercialization.

With a continued concentrate on disciplined capital allocation, MVMD intends to prioritize low-capital, royalty-based licensing alternatives for Soluvec™ 1% moderately than direct funding in manufacturing or market buildout. On this context, administration has initiated discussions with potential new licensees in Latin America, the place demand for scalable and cost-effective husbandry and aquaculture well being options stays important and the place the Firm’s patent technique helps future business growth.

International curiosity in Soluvec™ continues in administration’s view, supported by the Firm’s peer-reviewed information demonstrating improved bioavailability, efficacy, and stability relative to standard ivermectin formulations. Whereas the Firm doesn’t anticipate near-term materials revenues till further licensing preparations are secured, MVMD believes {that a} extra selective and partner-aligned strategy can higher place Soluvec™ for sustainable royalty development over time.

“Soluvec™ stays an essential asset for the Firm, and we’re working to align it with companions who can advance this chance successfully as we transfer into 2026,” Hancock added.

ABOUT MOUNTAIN VALLEY MD HOLDINGS INC.
Mountain Valley MD is constructing a world-class group centered across the implementation, licensing and reselling of key applied sciences and formulations:

  • patented Quicksome™ oral formulation and supply applied sciences,

  • patented Quicksol™ solubility formulation know-how

  • licensed product reseller of Agrarius™, a novel agricultural plant signaling know-how

In keeping with its imaginative and prescient in direction of “Extra Life”, MVMD applies its owned and licensed applied sciences to its work for superior supply of molecules for human and husbandry animal functions, together with the event of merchandise for ache administration, weight reduction, vitality, focus, sleep, nervousness, and extra. Moreover, MVMD’s work with Agrarius is concentrated on producing a constructive impression on crop yields and lowering fertilizer utilization.

MVMD’s patented Quicksome™ know-how makes use of proprietary formulations and stabilizing molecules to encapsulate and formulate energetic components into extremely environment friendly product codecs. The result’s a brand new era of product formulations that could possibly be able to delivering nutraceutical and drug molecules into the physique quicker, with larger impression, effectivity and accuracy.

MVMD’s patented Quicksol™ know-how covers all extremely solubilized macrocyclic lactones that could possibly be successfully utilized in a number of viral functions that would positively impression human and animal well being globally.

MVMD’s licensed Agrarius™ agricultural plant signaling know-how is designed to be utilized to crops to naturally improve yields, scale back fertilizer utilization, and improve common resilience to pests and local weather change.

For extra Firm info and phone particulars, go to www.MVMD.com.

CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING INFORMATION

Sure statements contained on this information launch might represent forward-looking info. Ahead-looking info is commonly, however not at all times, recognized by way of phrases resembling “anticipate”, “plan”, “estimate”, “anticipate”, “might”, “will”, “intend”, “ought to”, and comparable expressions. Ahead-looking info entails recognized and unknown dangers, uncertainties and different components which will trigger precise outcomes or occasions to vary materially from these anticipated in such forward-looking info.

The Firm’s precise outcomes may differ materially from these anticipated on this forward-looking info on account of regulatory choices, aggressive components within the industries by which the Firm operates, prevailing financial circumstances, and different components, lots of that are past the management of the Firm.

The Firm is making forward-looking statements, together with however not restricted to: the continued development of the Firm’s strains of enterprise; anticipated license preparations and launches and the timing thereof with regard to the Firm’s Quicksome™ know-how; continued trials and anticipated outcomes of the Firm’s licensed Agrarius™ product and the timing thereof; and the securing of further licensing preparations, and the construction and timing thereof, relating to the Firm’s Soluvec™ product.

The Firm believes that the expectations mirrored within the forward-looking info are cheap, however no assurance might be on condition that these expectations will show to be right and such forward-looking info shouldn’t be unduly relied upon. Any forward-looking info contained on this information launch represents the Firm’s expectations as of the date hereof and is topic to vary after such date. The Firm disclaims any intention or obligation to replace or revise any forward-looking info whether or not on account of new info, future occasions or in any other case, besides as required by relevant securities laws.

Neither the CSE nor OTC has reviewed or authorised the contents of this press launch.

View supply model on businesswire.com: https://www.businesswire.com/information/residence/20251224207390/en/

Contacts

Dennis Hancock
President and Chief Govt Officer
Mountain Valley MD Holdings Inc.
Investor Relations @ 647-725-9755
Electronic mail: information@mvmd.com
www.MVMD.com



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